Friday 3 October 2014
Optimizing DC cross-presentation: Orchestrating the immune response
Promotor: Prof. dr E.E.S. Nieuwenhuis
Defence: 3 October 2014
This thesis describes new insights in dendritic cell biology and contains disquisitions on antigen processing and presentation as well as the manipulation of these mechanisms using receptor mediated uptake. The work is aimed at better understanding dendritic cell (DC) biology, thereby contributing to pre-clinical work on DC vaccinations, which are being developed by the Utrecht Dendritic cells Against CancEr (U-DANCE) group.