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Cornelis van Tilburg

Tuesday 22 March 2011

Immunity and infectious morbidity in childhood ALL treatment

Promotor: Prof.dr E.A.M. Sanders
Defence: 22 March 2011
Full text

Levels of T and B cell subpopulations together with immunoglobulin and specific antibody concentrations are less affected by reduced intensity chemotherapy which is reflected in a major reduction in infectious morbidity. However, the beneficial effect of treatment reduction on specific antibody levels seems, although significant, only marginal. The same applies to the long term recovery of the immune system.